“.....
allow the creation of embryos for scientific research – and under very strict
conditions to give people the possibility of (healthy) children....... The
research has to do with infertility, artificial reproduction techniques and hereditary
or congenital diseases”
Dutch Health Minister,
Edith Schippers on changes coming to Netherlands law relating to embryonic
research
Human
cloning may be happenings sooner than we thought. The need to improve
invitro-fertilization may be driving us towards this lofty goal.
The
Government of the Netherlands has announced changes on its laws on embryonic
research as reported in the article “Netherlands
gives green light for growing human embryos”, published Saturday 28 May
2016, Agence France-Presse.
Up until now, most embryonic research has been conducted on leftover embryos from invitro-fertilization. The new rules mean that researcher can now growing human embryos “under strict and limited conditions” for scientific research.
Possibly
too, they may also be able to solicit embryos from sources other than those
leftover from invitro-fertilization such as from women who submit their ova for
experimental trials under contract.
Effectively,
ova submitted from a ova bank much the same way Jamaican men can donate sperm
to a Sperm bank as explained in my blog article
entitled “How
US$1500 monthly from HWFMU helps College Jamaican Males impregnate Professional
Women” for research purposes.
Netherlands and CRISPR-Cas9
- Prevent hereditary or congenital diseases by editing DNA
It
would also allow them leeway to do research into combating hereditary disease,
most likely via using CRISPR-Cas9 (clustered regularly interspaced short
palindromic repeat).
CRISPR-Cas9 is a protein that is derived from
a bacteria, Cas9 which can be used to splice in a new DNA strand at a specific
point in DNA molecule in a Genome. The video below explains it a bit better.
Already,
since January 2016, Britain has given permission to Dr. Kathy Niakan and her
team at the Francis Crick Institute to edit the human genome using CRISPR-Cas9
as I'd reported in my blog article
entitled “Why
Dr. Kathy Niakan of Francis Crick Institute Gene Editing means Automated Human
Birth”.
The
Netherlands also has similar aims and may even use CRISPR-Cas9 to edit the
human genome to prevent hereditary or congenital diseases. So why are the Dutch
interested in reducing infertility and research into artificial reproduction
techniques?
Dutch law and Genetic
Research – Improvements needed to make invitro-fertilization more efficient
First,
the decision for changing Dutch law to allow the growing human embryos “under
strict and limited conditions” for scientific research.
That
means no embryos under experimental conditions surviving beyond 14 days, a
preset arbitrary limit that can be overcome by accelerating the growth of the fertilized
ovum using time-warping technology…more on that in another article. For now,
scope out this Ted-Ed Video on Invitro-Fertilization.
The
reason for the Dutch decision is that it'll give scientists access to the freshest
ova and sperm possible to conduct research onto invitro-fertilization, as those
left-over from invitro-fertilization may be damaged during the freezing
process. The use of leftover ova was always possible, ironically due to the
poor success rate of invitro-fertilization.
During
the first week after fertilization, the sperm-ova amalgam forms a blastocyst,
the 200- to 300-cell structure critical to human development. However only 50%
of fertilized ovum becomes blastocysts after invitro-fertilization.
Of that number, only 50% can be implanted into the womb of the egg donor. Even after that, only 50% make it past 3 months. To put that in numbers, of 100 ovum used in invitro-fertilization, only 13 ever have the potential to become babies.
This
means a lot of ova contributed form a single woman are wasted because the
science to fertilize ova outside of the womb, invitro-fertilization, is nowhere
near as perfect at simulating the conditions within the womb for the storage of
ova.
Scientists
suspect that may be the reason why invitro-fertilization has such a high
failure rate among geneticists, as no-one genetics lab experimenting with
leftover ova has ever managed to get them to live beyond the stipulated 14 day
rule imposed by medical science researchers.
Dutch and CRISPR-Cas9 –
Humans in the future to be grown artificially out of the womb
For
this reason, research into simulating the perfect conditions for
invitro-fertilization may lead to the creation of artificial wombs as argued in
my blog article
entitled “University
of California CRISPR-Cas9 Human Organs in Pigs means Human Chimeras Possible”.
This
research using CRISPR-CaS9 is not just aimed at improving the success rate of
invitro-fertilization. In the long run, it aims to eliminate hereditary or
congenital diseases and ushering in the developement of artificial wombs to
grow babies outside of the womb.
Thus
in the Future, humans would not be born....they could be grown and ordered,
prefect and free of genetic defects.
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